鹤天赐 饰演 李修文安淇同学，暗恋安淇，从加拿大追随到马六甲去。直肠直肚，常闹笑话，对安淇关怀备至。
Nat Ho as Li Xiuwen
Xiuwen is Anqi’s classmate and has a secret crush on her. He is a straightforward and witty young man who takes very good care of Anqi, and pursues her from Canada to Malacca.

陈靓瑄 饰演 安淇月娘孙女，加拿大留学生，因感情波折，避居马六甲月娘家。听祖母月娘说起许多她从来不知的往事，并从月娘身上学到面对问题，解决问题。
Felicia Chin as Anqi
She is Yueniang’s granddaughter and a graduate from Canada. She escapes to Yueniang’s home in Malacca after some romantic setbacks and begins to learn from her grandmother many things that she has never heard of before. From there, she learns to face her problems and solve them.

章缜翔 饰演 罗伯张查里张儿子，留洋英国，阴险狡诈，强暴玉珠后娶进门，折磨至死。本以为没有手尾，不料月娘追查玉珠死因，要他受法律制裁。恨月娘入骨，欲置她于死地。
Zzen as Robert Zhang
Charlie Zhang’s son studied in England and is a cunning one like his father. After marrying Yuzhu, he tortures her to death and believes it was a clean job. Unexpectedly, Yueniang searches for the cause of Yuzhu’s death and is adamant on bringing justice to Robert. Thus, Robert hates Yueniang vehemently and is bent on killing her.

沈金兴 饰演 查里张富豪名望峇峇家族后代，却全盘西化，瞧不起峇峇传统。势利商人，为达目的不择手段，喜欢玩弄女人。
Desmond Sim as Charlie Zhang
Though a descendent of an affluent Peranakan family, Charlie is Westernised and despises the Baba tradition. A shrewd businessman, he goes to unscrupulous means to get his way and has no qualms making use of women.

潘玲玲 饰演 秀凤金成妻子。一切以桂花惟命是从，想方设法让两个女儿嫁入豪门，甚至不惜牺牲月娘。发现自己丈夫与妹妹私通，晴天霹雳，跳井自杀。
Pan Lingling as Xiufeng
Wife to Jincheng, Xiufeng listens to her mother-in-law’s every word. She will do whatever she can to marry her two daughters off to wealthy families, even if it’s at Yueniang’s expense. She suffers a terrible shock when she finds out that her husband is having a clandestine affair with her sister Xiujuan.

黄慧 饰演 阿桃黄家女佣，是梳起不嫁的妈姐，常讲错话、闹笑话。她与黄菊香情同姐妹，后来为了给黄菊香送嫁妆，一只脚被打瘸。与月娘的感情更深，一直追随着月娘，年届90岁，仍不离不弃。
Huang Hui as Ah Tao
Ah Tao is the maid of the Huangs who often says the wrong things and becomes a laughing stock. She is very close to Juxiang and her daughter, Yue Niang. Later, while she is delivering Juxiang’s dowry, she is beaten up and becomes lame. A loyal maid, she follows Yue Niang all the way till she is 90 and still refuses to leave her.

陈邦鋆 饰演 黄天宝黄金成和秀凤的长子，眼高手低，成事不足败事有余，想叱咤商场，却没有才能，只能跟在罗伯张屁股后当跑腿。
Andie Chen as Huang Tian Bao
He is the eldest son of Huang Jin Cheng and Xiu Feng. He often has great ambitions but has little talent. He wants to control the entire business industry but has limited capability. Ultimately, he is only the helper of Robert Zhang.

林明伦 饰演 黄金成黄元与桂花的儿子。个性平庸怕事，原本喜欢秀娟，却被安排与秀娟的姐姐秀凤结婚。后来重遇从英国回来的秀娟，两人有染，还亏空公款与秀娟远走高飞，导致黄家破产。
Darren Lim as Huang Jin Cheng
He is the son of Huang Yuan and Gui Hua. His character is indifferent and afraid of trouble. Originally, he likes Xiu Juan but is arranged to marry her sister, Xiu Feng instead. Later in the show, he causes the Huangs to be bankrupt after he elopes with Xiu Juan who later came back from England.

李茵珠 饰演 陈老太非常注重传统，是陈家的“老太君”，大家都听她的。对陈家男丁单薄忧心忡忡，所以，很重视陈锡（戚玉武饰）的婚姻大事。她亲自给陈锡选妻，要找一个名副其实的娘惹。
Li Yin Zhu as Chen Lao Tai
Chen Lao Tai emphasizes a lot on tradition and makes the ultimate decision is the Chen family. Everyone obeys and respects her. She is especially worried about her eldest grandson marriage and allows him to choose his own wife who must be a Peranakan.

向云 饰演 天兰黄菊香之母，原为黄家佣人，被黄元看上，纳为小妾。因生了聋哑的黄菊香，饱受歧视，加上出身低微，让她自惭形秽，表面上是黄家二太太，实则与佣人无异。
Xiang Yun as Tian Lan
The mother of Juxiang, she is a maid of the Huangs. She later marries Huang Yuan as a mistress. Giving birth to a deaf-mute Juxiang causes her to be looked down upon and is frequently discriminated. Although she is the second wife in the family, her status in the family is of no difference as the maid.

方展发 饰演 陈盛陈锡的小叔叔，玩世不恭，有正义感，注重保留峇峇文化。喜欢菊香（欧萱饰），却被逼娶自己没感觉的美玉（洪乙心饰）。整天在外跳舞唱班顿，过着醉生梦死的生活。
Pierre Png as Chen Sheng
The youngest uncle of Chen Yi, he is frivolous yet likes to uphold justice. Chen Sheng sees the need to preserve the Peranakan culture and likes Juxiang. However, he is forced to marry Mei Yu instead. As he has no feelings for Mei Yu, he spends his days away dancing and singing Malay poems outside after marriage.

姚玟隆 饰演 刘一刀杀猪为生，一把杀猪刀不离手，刀出如飞。刘一刀理光头，喜欢打赤膊，虽然话不多，但言出必行。他与妈妈相依为命，非常孝顺，对妈妈言听计从。妈妈看中月娘，临终前要他娶月娘为妻，他遂上门求亲。她拒绝，他竟打死一只老虎以表自己的决心。月娘誓死不从，后来两人结为兄妹，刘一刀更在月娘协助下成为富商。
Yao Wen Long as Liu Yi Dao
Liu Yi Dao is a butcher who cannot part with his knife. He is bald and likes to go around without a shirt. He is a man of a few words but is very loyal and keeps to his words. He is a filial child who lives with his mother and obeys whatever his mum says. His mum later likes Yue Niang and wants her to be her daughter-in-law. He tries to court Yue Niang to no avail. To prove his sincerity towards her, he even kills a tiger. Yue Niang refuses to budge and the two become sworn siblings instead. With the help of Yue Niang, Yi Dao later becomes a wealthy businessman.

林梅娇 饰演 桂花黄元（严丙量饰）的元配，为人妒嫉心重、恶毒，视黄菊香母女为眼中钉，后更把月娘当佣人使唤，动不动就打骂她。
Lin Mei Jiao as Gui Hua
She is evil and easily jealous. Gui Hua hates Juxiang and treats her daughter Yue Niang as a maid. She often scolds and beats her.

许美珍 饰演 秀娟个性西化、时髦，言行举止大胆。喜欢上金成（林明伦饰），但却无法和他在一起。后来远赴英国，嫁给英国人，没想到以离婚收场，回来投靠姐姐秀凤（潘玲玲饰），却与金成暗度陈仓，还鼓动他卷走公司巨款。
Cynthia Koh as Xiu Juan
She is the younger sister of Xiu Feng (played by Pan Ling Ling) and fancies Jin Cheng (played by Darren Lim).

洪乙心 饰演 黄美玉她是黄家的长女，也是陈盛(方展发饰)的妻子。婚后一直无法获得陈盛欢心，导致她郁郁寡欢。后来，她为了黄家，想办法让陈锡和黄珍珠（郭蕙雯饰）结婚；后来为了阻止月娘和陈锡在一起，企图把月娘溺死在井里。
Apple Hong as Huang Meiyu
As the eldest daughter of the Huangs, she is also the wife of Chen Sheng (played by Pierre Png). Unfortunately, Chen Sheng does not exactly fancy her despite after marriage. Feeling a little depressed, she also plays a part in breaking Yue Niang and Chen Xi…

郭蕙雯 饰演 黄珍珠自私善妒，常发小姐脾气，为了嫁给陈锡，对月娘下毒手，将她推入井里。后来亲眼目睹妹妹黄玉珠被罗伯张强暴，也愿意出手相救。后来得尝所愿嫁入陈家，却无法得到丈夫的爱，最终沦落为吧女。
Eelyn Kok as Huang Zhenzhu
Zhenzhu is a selfish and pampered girl who resorts to dirty tricks on Yue Niang in order to marry Chen Xi. When she witnessed her sister Yuzhu was raped by Robert, she refuses to save her. She finally gets to marry Chen Xi, but is unable to secure a place in his heart…

白薇秀 饰演 黄玉珠外表清秀温柔，心地善良，和月娘情同姐妹，教她读书识字。虽对陈锡有好感，但当她知道陈锡心中喜欢的是月娘，反而撮合二人。不幸被罗伯张强暴，被逼嫁入张家，饱受罗伯张虐待，最后更精神崩溃。
Joanne Peh as Huang Yuzhu
A kind and gentle girl who is best friend to Yue Niang, Yuzhu also teaches Yue Niang to read and write. Although she also fancies Chen Xi, she knows that she has no place in his heart except for Yue Niang. Instead, she tries to matchmake them. She later goes into depression after having to marry a man she doesn’t like as she was raped by him…

戚玉武 饰演 陈锡名门之后，也是家族中的三代单传，背负传递香火与振兴家族生意的重任。陈锡年轻有为，善于经营，对感情执着。早年负笈英国，受西方自由主义影响，面对保守的峇峇家庭，不免有冲突。后来在家族的压力下，无法与月娘结婚，黯然抛下没有感情的妻子黄珍珠和家族事业，悄然而别，从此音讯全无，生死未卜。
Qi Yuwu as Chen Xi
Yuwu is the male lead in The Little Nyonya. Young and capable, his character Chen Xi manages his family business well. He has frequent clashes with his Peranakan culture as he was once lived in England, which gave him more freedom. Due to his family, he is unable to marry the woman of his dreams Yue Niang and decides to leave everything behind including his legitimate wife Huang Zhen Zhu (played by Eelyn Kok), family and his business.

戴阳天 饰演 山本洋介年轻日籍摄影师，在新加坡开了一间小影室。本性善良，乐于助人。因无意中拍下菊香的倩影，爱上菊香，后来还帮助她摆脱奸商查里张。二人婚后生下月娘。回乡探父之病被抓去当兵，从战场逃走，辗转回来找菊香。日军南侵，为保护菊香母女，逃兵身份败露，被枪杀。
Dai Yang Tian as Yamamoto Yousuke
Yamamoto Yousuke is a young Japanese photographer who opens a small photo studio in Singapore . He is kind-hearted and helpful. He falls in love with Juxiang after taking a shot of her unintentionally. Yousuke also helps Juxiang to break away from unscrupulous businessman Charlie Zhang. The two later get married and have a daughter, Yue Niang. While he returns to his hometown to visit his ailing father, he is forced to be a soldier. He then escapes from the war and returns to find Juxiang. Unfortunately, the Japanese make their way to conquer South East Asia . In order to protect both his wife and daughter, he is caught for escaping army and is killed by the Japanese.

欧萱饰演 - 黄菊香（母亲） 黄菊香自幼聋哑，长得漂亮。自小在母亲调教之下，煮得一手好菜，珠绣手艺也非常特出。她外柔内刚，不愿嫁给奸商当填房，离家出走，受尽磨难，后来嫁给一日本摄影师　洋介（戴阳天饰），产下女儿月娘（欧萱分饰）。后来洋介被逼从军，黄菊香独立抚养女儿。日据时代，她不幸死于战乱中。
欧萱分饰 - 山本月娘（女儿） 月娘和母亲黄菊香长得如一模子印出来，她也继承了母亲坚忍不拔的性格。母亲死后，她寄住在外婆（向云饰）家，学得一手好厨艺和女红。虽然月娘在黄家饱受欺凌，她却乐观以对。后来，她爱上名门之后陈锡（戚玉武饰），但却被逼嫁给流氓头子刘一刀（姚玟隆饰）。怎知道她反与刘一刀结成兄妹，学做生意有成，还反过来挽救破产的家族。
Jeanette Aw as Huang Juxiang and Yue Niang
She has to portray two different characters in the drama – Huang Juxiang (Mother) and Yue Niang (Daughter). Huang Juxiang is not easy to play because she is deaf-mute though very pleasant looking. Huang Juxiang is also a virtuous woman who is excellent at cooking and sewing. Later in the show, she marries a Japanese photographer (played by Dai Yang Tian) and gives birth to Yue Niang (also played by Jeanette).
Yue Niang looks exactly like her mother and takes after her positive traits. Also a good cook, she stays at her grandmother's house (played by Xiang Yun) after the death of her mother. Her love interest is Chen Xi (played by Qi Yuwu) but was forced to marry Liu Yi Dao instead (played by Yao Wen Long). Unexpectedly, she becomes sworn siblings with Yi Dao and helped to save the family's declining business.